Gene information
Official symbol KLK3
Official full name kallikrein related peptidase 3
Gene type protein-coding gene
Chromosome19q13.33
Alias symbolPSA
Previous symbolAPS
Gene familyKallikreins
Resources
Entrez Gene 354
HGNC HGNC:6364
Ensembl ENSG00000142515
Vega OTTHUMG00000182867
UCSC uc021uyi.2
GO terms: 18 records
GO Description Category LogP Number of genes Detail
GO:0002697 regulation of immune effector process GO Biological Processes -33.2683521 48 More
GO:0002700 regulation of production of molecular mediator of immune response GO Biological Processes -19.7615296 26 More
GO:0002831 regulation of response to biotic stimulus GO Biological Processes -10.931136 25 More
GO:0002920 regulation of humoral immune response GO Biological Processes -5.73581155 7 More
GO:0003013 circulatory system process GO Biological Processes -65.2875605 130 More
GO:0003073 regulation of systemic arterial blood pressure GO Biological Processes -22.2238525 34 More
GO:0008015 blood circulation GO Biological Processes -65.7270163 119 More
GO:0008217 regulation of blood pressure GO Biological Processes -35.2019435 60 More
GO:0016525 negative regulation of angiogenesis GO Biological Processes -31.9326641 51 More
GO:0017171 serine hydrolase activity GO Molecular Functions -24.8900503 32 More
GO:0031347 regulation of defense response GO Biological Processes -64.5971043 148 More
GO:0031349 positive regulation of defense response GO Biological Processes -32.1301903 71 More
GO:0032103 positive regulation of response to external stimulus GO Biological Processes -58.7273809 118 More
GO:0045765 regulation of angiogenesis GO Biological Processes -63.6171248 109 More
GO:0050778 positive regulation of immune response GO Biological Processes -17.2528761 40 More
GO:1901342 regulation of vasculature development GO Biological Processes -64.8504074 111 More
GO:1901343 negative regulation of vasculature development GO Biological Processes -32.5354692 52 More
GO:2000181 negative regulation of blood vessel morphogenesis GO Biological Processes -32.6997315 52 More
KEGG pathways: 1 record
KEGG Description Category LogP Number of genes Detail
hsa05200 Pathways in cancer KEGG Pathway -30.6393212 92 More
Drug-Gene interaction
view
Related drugs: 18 records
Drug name Interaction type Source PMID View
abarelix NCI 11342922 view
androstenedione NCI 8907816 view
aprotinin inhibitor ChemblInteractions view
bicalutamide NCI 10075669 view
docetaxel NCI 1068798815864591 view
ecallantide inhibitor ChemblInteractions view
estramustine NCI 11391599 view
etoposide NCI 11391599 view
flutamide NCI 7541862 view
genistein NCI 10811979 view
mifepristone NCI 905241415308689 view
nilutamide NCI 9186345 view
octreotide NCI 7515212 view
progesterone NCI 9052414 view
selenomethionine NCI 12539231 view
tamoxifen NCI 7532467 view
topsalysin TdgClinicalTrialTTD view
vinblastine NCI 1371564 view
Related study: 1 record
Molecular factor Omics type Application Objective MI type Reference
prostate-specific antigen proteomics non-ST elevation myocardial infarction[diagnosis] non-ST elevation myocardial infarction Patane S et al. Int J Cardiol. 2012
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